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3D Culture in Functionalized FN-Silk Networks Facilitate Proliferation, Differentiation and Phenotypic Stability of Mature Human Primary Cells and Stem Cells
Källén, A., Taebnia, N., Widhe, M., Lauschke, V. M. and Hedhammar, M. (2025) Biotechnology and Bioengineering. https://doi.org/10.1002/bit.70002
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Site-specific Functionalization of Recombinant Spider Silk Using Enzymatic Sortase Coupling
Pasupuleti, R., Jansson, R., Isacsson, I., Hogan, F., Widhe, M. and Hedhammar, M. (2025) ACS Omega, 10, 6, 5943-5952 https://doi.org/10.1021/acsomega.4c09900
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A Fibronectin (FN)-Silk 3D Cell Culture Model as a Screening Tool for Repurposed Antifibrotic Drug Candidates for Endometriosis
Teworte, S., Behrens, C. M., Widhe, M., Gurzeler, L-A., Hedhammar, M. and Luciani, P. (2025) Small, 2409126 https://doi.org/10.1002/smll.202409126
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Standalone single- and bi-layered human skin 3D models supported by recombinant silk feature native spatial organization
Gkouma, S., Bhalla, N., Frapard, S., Jönsson, A., Gürbüz, H., Dogan, A. A., Giacomello, S., Dufva, M., Ståhl, P. L., Widhe, M. and Hedhammar, M. (2025) Biofabrication, 17, 1, 015015 https://doi.org/10.1088/1758-5090/ad8b72
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Nanofibrillar Basement Membrane Mimic Made of Recombinant Functionalized Spider Silk in Custom-Made Tissue Culture Inserts
Gustafsson, L., Gkouma, S., Jönsson, A., Dufva, M., Hedhammar, M. (2024) J. Vis. Exp. (213), e67116 https://doi.org/10.3791/67116
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Structural conversion of the spidroin C-terminal domain during assembly of spider silk fibers
De Oliveira, H. D., Gowda, V., Sparrman, T., Gustafsson, L., Pires, S. R., Riekel, C., Barth, A., Lendel, C. and Hedhammar, M. (2024) Nature Communications, 15, 4670 https://doi.org/10.1038/s41467-024-49111-5
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Self-Assembly of RGD-Functionalized Recombinant Spider Silk Protein into Microspheres in Physiological Buffer and in the Presence of Hyaluronic Acid
Ornithopoulou, E., Åstrand, C., Gustafsson, L., Crouzier, T. and Hedhammar, M. (2023) ACS Appl. Bio Mater., 6, 9, 3696-3705 https://doi.org/10.1021/acsabm.3c00373
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In vitro Blood-Brain barrier model based on recombinant spider silk protein nanomembranes for evaluation of transcytosis capability of biomolecules
Hjelm, L.C., Hedhammar, M. and Löfblom, J. (2023) Biochem. and Biophys. Res. Com., 669, pp 77-84 https://doi.org/10.1016/j.bbrc.2023.05.093
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Development and characterization of a recombinant silk network for 3D culture of immortalized and fresh tumor-derived breast cancer cells
Collodet, C., Blust, K., Gkouma, S., Ståhl, E., Chen, X., Hartman, J. and Hedhammar, M. (2023) Bioeng. Transl. Med., 2023;e10537 https://doi.org/10.1002/btm2.10537
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Silk Assembly against Hydrophobic Surfaces─Modeling and Imaging of Formation of Nanofibrils
De Oliveira, H. D., Biler, M., Mim, C., Enstedt, L., Kvick, M., Norman, P., Linares, M. and Hedhammar, M. (2023) ACS Appl. Bio Mater., 6, 3, 1011-1018 https://doi.org/10.1021/acsabm.2c00878